Siddharth R. Krishnan, PhD

Publications | Patents | Awards | Selected Press | Contact

My research focuses on developing novel soft materials and device architectures for biomedical sensors and drug delivery. I am currently a postdoctoral fellow in Prof. Daniel Anderson and Prof. Robert Langer’s group at MIT/Boston Children’s Hospital. I received my PhD in Materials Science and Engineering from the University of Illinois at Urbana-Champaign, under Prof. John Rogers, and was a visiting fellow at Northwestern University, at the Querrey-Simpson Insitute for Bioelectronics, from 2016-2019. I am also a co-founder of Rhaeos, a company spun out from my PhD research in wearable sensors for patients with hydrocephalus. I received my BS and MS in Mechanical Engineering from Washington University in St. Louis.

1. Krishnan, S.R ϯ, Arafa, H ϯ., Kwon, K.ϯ, Su, C.J. ϯ, Wang, H. ϯ, Deng, Y., Murthy, N., Chen, H-M., Loza, J., Reeder, J., Freudman, J., Stankiewicz, I., Banks, A., Huang, Y., Alden, T., Potts, M., Ayer, A., Rogers, J.A, Continuous, noninvasive wireless monitoring of flow of cerebrospinal fluid through shunts in patients with hydrocephalus. npj  Digital Medicine,(3), 29 2020.  (Front Banner Image).

2. Krishnan, S.R ϯ, Ray, T.R ϯ., Ayer, A.B ϯ., Ma, Y., Gutruf, P., Lee. K., Lee, J., Wei, C., Feng, X., Ng, B., Abecassis, Z., Murthy, N., Stankiewicz, I., Freudman, J., Stillman, J., Kim, N., Young, G., Goudeseune, C., Ciraldo, J., Tate., Huang, Y., Potts, M., Rogers, J.A, Epidermal electronics for the noninvasive, wireless, quantitative assessment of ventricular shunt function in patients with hydrocephalus  Science Translational Medicine10, 465 2018.  (Front banner image)

3. Krishnan, S.R., Su, C.J., Xie, Z., Patel, M., Madhvapathy, S.R., Xu, Y., Freudman, J., Ng, B., Heo, S.Y., Wang, H. and Ray, T.R., Leshock, J., Stankiewicz, I., Feng, X., Huang, Y., Gutruf, P., Rogers, J.A,  Wireless, Battery‐Free Epidermal Electronics for Continuous, Quantitative, Multimodal Thermal Characterization of Skin. Small, p.1803192. 2018 (Cover).

4. Krishnan, S.R ϯ.; Shi, Y ϯ.; Webb, R. C, Ma, Y., Bastien, P., Crawford, K., Wang, A., Feng, X., Manco, M., Kurniawan, J., Tir, E., Huang, Y., Balooch, G., Pielak, R., Rogers, J.A Multimodal epidermal devices for hydration monitoring. Microsystems & Nanoengineering 3, 17014 2017.

5. Krishnan, S.R., Kumfer, B. M.; Wu, W.; Li, J.; Nehorai, A.; Axelbaum, R. L., An Approach to Thermocouple Measurements That Reduces Uncertainties in High-Temperature Environments. ACS Energy & Fuels 2015.

6. Webb, R. C. ϯ; Ma, Y. ϯ; Krishnan, S.R. ϯ, ,Yoon, S., Guo, S., Feng, X., Shu, Y., Seidel, M., Cho, N.H., Kurniawan, J., Ahad, J., Sheth, N., Kim, K., Taylor, J.G, Darlington, T., Chang, K., Huang, W., Ayers, J., Gruebele, A., Pielak, R., Slepian, M.J, Huang, Y., Gorbach, A., Rogers, J.A Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow. Science Advances 1 (9), e1500701 2015.

7. Reeder, J.T., Xue, Y., Franklin, D., Deng, Y., Choi, J., Prado, O., Kim, R., Liu, C., Hanson, J., Ciraldo, J., Bandodkar, A.J., Krishnan, S.R, et. al, Resettable, Skin-Interfaced Microfluidic Sweat Collection Devices with Chemesthetic Hydration Feedback Enabled by Soft, Monolithic Valves and Pumps. Nature Communications 10 (5513), 2019

8. Zhang, Y., Mickle, A.D., Gutruf, P., McIlvired, L., Guo, H., Wu,Y., Golden, J., Xue, Y., Grajales-Reyes, J.P., Wang, X.,    Krishnan, S.R, Xie, Y., Peng, D., Su, C-J., Zhang, F., Reeder, J.T., Vogt, S.K., Huang, Y., Rogers, J.A, Gereau, R.W, Soft, fully implantable optofluidic cuff systems for wireless optogenetic and pharmacological neuromodulation of peripheral nerves eeaw5296 Science Advances 2019

9. Gutruf, P., Krishnamurthi, V, Vazquez-Guardado, A., Xie, Z., Banks, A., Su, C., Xu, Y., Haney, C.R, Waters, E., Kandela, Krishnan, S.R, Ray, T.R, Leshock, J.P., Huang, Y., Chanda, D., Rogers, J.A, Advanced, Fully Implantable Optoelectronic Systems for Battery-free Multimodal Operation in Neuroscience Research,1,652 -660 Nature Electronics 2018. (Cover)

10. Ray, T.R., Choi, J., Bandodkar, A., Krishnan, S.R., Gutruf, P., Tian, L., Ghaffari, R., Rogers, J.A, Recent advances in Bio-Integrated Sensors Chemical Reviews 119, 5461-55332019

11. Bandodkar., A.J.,Gutruf, P., Choi, J., Lee, K., Sekine, Y., Reeder, J.T., Jeang, W.J., Aranyosi, A.J., Lee, S.P., Model, J.B., Ghaffari,R., Su, C., Leshock, J.P., Ray, T.R., Verrillo, A., Thomas, K., Krishnamurthi, V., Han, S., Kim, J., Krishnan, S.R., Hang, T., Rogers, J.A  Battery-free, skin-interfaced microfluidic/electronic system for simultaneous electrochemical, colorimetric & volumetric sweat analysis, Science Advances 5:eeav3294 2019

12. Reeder, J., Choi, J., Xue, Y., Gutruf, P., Hanson, J., Liu, M., Ray, T., Bandodkar, A., Avila, R., Xia, W., Krishnan, S.R, Xu, S., Barnes, K., Pahnke, M., Ghaffari, R., Huang, Y., Rogers, J.A  Waterproof, Electronics-Enabled, Epidermal Microfluidics for Sweat Collection, Biomarker Analysis and Thermography in Aquatic Settings, Science Advances, 5:eeau6356 2019

13. Crawford, K. E., Ma, Y., Krishnan, S.R., Wei, C., Capua, D., Xue, Y., Xu, S., Xie, Z., Won, S.M., Tian, L., Webb, R.C, Li, Y., Feng, X., Huang, Y., Rogers, J.A., Advanced approaches for quantitative characterization of thermal transport properties in soft materials using thin, conformable resistive sensors. Extreme Mechanics Letters 2018(Cover).

14. Madhvapathy, S. R., Ma, Y., Patel, M., Krishnan, S.R., Wei, C., Li, Y, Xu, S., Feng, X., Huang, Y., Rogers, J. A. Epidermal Electronic Systems for Measuring the Thermal Properties of Human Skin at Depths of up to Several Millimeters. Advanced Functional Materials, 1802083. 2018 (Cover).

15. Tian, L.; Li, Y.; Webb, R. C.; Krishnan, S.R,  Bian, Z., Song, J., Ning, X., Crawford, K., Kurniawan, J., Bonifas, A., Ma, J., Liu, Y., Xie, X., Chen, J., Liu, Y., Shi, Z., Wu, T., Ning, R., Li, D., Sinha, S., Cahill, D.G., Huang, Y., Rogers, J.A, Flexible and Stretchable 3ω Sensors for Thermal Characterization of Human Skin. Advanced. Functional. Materials. 27, 17012822017 (Cover).

16. Webb, R. C.; Krishnan, S.R.; Rogers, J. A., Ultrathin, Skin-Like Devices for Precise, Continuous Thermal Property Mapping of Human Skin and Soft Tissues. In Stretchable Bioelectronics for Medical Devices and Systems, Springer: pp 117-132 2016;.

17. Zhang, Y.; Chad Webb, R.; Luo, H.; Xue, Y.; Kurniawan, J.; Cho, N. H.; Krishnan, S.R.; Li, Y.; Huang, Y.; Rogers, J. A., Theoretical and Experimental Studies of Epidermal Heat Flux Sensors for Measurements of Core Body Temperature. Advanced healthcare materials 5 (1), 119-127 2016 (Cover)

Google Scholar

Patent Applications

1.Rogers, J.A., Webb, R.C., Krishnan, S., Balooch, G. and Pielak, R.M., THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS and L’OREAL, 2017. Thermal Transport Characteristics of Human Skin Measured In Vivo Using Thermal Elements. U.S. Patent 20,170,347,891

2. Rogers, J.A., Krishnan, S., Ray, T.R., Ayer, A.B., Gutruf, P., Wireless and Noninvasive Epidermal Electronics, Provisional patent filed 62/650,826

3. Rogers, J.A, Xu, S., Li, Y., Madhvapathy, S.R., Gutruf, P., Krishnan, S., Wireless Skin Hydration Sensor with Methods and Uses, Provisional Patent Filed, 62/696,685

Awards and Honors

  • MIT Technology Review Innovators Under 35 (2020)
  • Forbes 30 under 30, Science (2020)
  • Silver Medal, Materials Research Society (2019)
  • Illinois Innovation Prize (2019)
  • Chakrapani innovation award for outstanding PhD thesis, University of Illinois at Urbana-Champaign (2019)
  • Cisco Global Problem Solver Prize (with Dr. Amit Ayer) (2019)
  • Finalist, Lemelson-MIT student prize, ‘Cure it’ category (2019)
  • Southwest Pediatric Device Consortium Prize (with Dr. Amit Ayer) (2019)
  • Ethan H. Shepley outstanding graduating senior award for leadership, scholarship and service to society, Washington University in St. Louis (2013)

Selected Press and Media

Profile, Innovators under 35, 2020 MIT Technology Review

Profile, 2020 30 under 30 in Science, Forbes Magazine

Skin sensor could improve life for a million hydrocephalus patients, Northwestern University

MatSE PhD student Siddharth Krishnan wins Illinois Innovation Prize, University of Illinois

IIP Provides Financial Boost to Innovative Medical Device Startup, University of Illinois at Urbana-Champaign

Wired In: Siddharth Krishnan, News-Gazette

Experimental skin sensor may warn of brain fluid problems, Reuters

Noninvasive wearable device monitors brain shunt function, WTTW Chicago

Flexible sensors measure blood flow under the skin, IEEE Spectrum

New Wearable Device Can Measure Your Blood Flow, MIT Technology Review

An Underwater Skin Sensor Lets Swimmers Track Their Sweat, Wired

Your sweat will see you now, New York Times

Cisco Awards Fourth-Annual Global Problem Solver Prize to Rhaeos, Inc. at the Rice Business Plan Competition, Cisco Systems


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